Upon graduation from the University at Albany, three members of the Epsilon Nu undergraduate chapter decided they wanted to continue their service within the Albany community through Zeta. In fall of 1990, Soror Cheryl Pemberton, Soror Mary Sydnor, and Soror Estella Bonay chartered Omicron Epsilon Zeta chapter as the graduate chapter designated to serve New York's Capital Region.

Since its inception, Omicron Epsilon Zeta has upheld the principals and ideals upon which Zeta Phi Beta Sorority was founded, thus making a tremendous impact in the immediate community through funding scholarships, sponsoring community events, hosting programs, and serving as the epitome of Finer Womanhood. The White Rose Scholarship Fund is Omicron Epsilon Zeta's signature feat developed by sorors as a means to accumulate and distribute funds to a deserving graduating high school female in the Capital Region.

Through the years, Omicron Epsilon Zeta has served as a temporary home to over three dozen women who have earned at least a Bachelor's degree, are sorority minded, and have a strong desire to plant the footsteps of Zeta Phi Beta Sorority, Incorporated within their community and beyond.